About Hyperbaric Oxygen Treatments (HBOT)
Supporting documents (classified chronologically)
Jonathan L. Halbach, James M. Prieto, Andrew W.
Wang, Dennis Hawisher, David M. Cauvi, Tony Reyes,
Jonathan Okerblom, Israel Ramirez-Sanchez, Francisco
Villarreal, Hemal H. Patel, Stephen W. Bickler, George
A. Perdrizet, and Antonio De Maio.
Sepsis is a major clinical challenge, with therapy limited
to supportive interventions. Therefore, the search for
novel remedial approaches is of great importance.
The authors addressed whether hyperbaric oxygen
therapy (HBOT) could improve the outcome of sepsis
using an acute experimental mouse model.
Khodor Haidar Hassan, Joelle Azzi, Gian Marco Oppo,
Hadi Raef Rida, Roberto Vecchioni, Mohamad Ali
Chahrour, Mehdi Raef Rida, Fadel Nahle, Hadi Farhat,
Edwin Parra Prada, and Ahmad Najib Ballout.
Hyperbaric Oxygen Therapy (HBOT) is a
recommended treatment for all hypoxic pathologies
and has been used for decades as a recommended
treatment for hypoxic-ischemic and infectious
The pressures utilized vary from 2.2 to 2.8 ATA. 20
Osteoporosis patients treated underwent HBOT at 1.5
ATA and 100% oxygen for 15 sessions.
Gordon Slater, Martin O’Malley, Tayla Slater, and
Hyperbaric Oxygen Therapy (HBOT) has been a
recognized treatment for a multitude of injuries for
decades and presents significant opportunities for the
improvement of wound healing, blood vessel
restoration, reduction in recovery time after surgery,
treatment of neurological and neurodegenerative
disorders, improvement of memory and cognition,
sports injury rehabilitation, cartilage regeneration, and
overall quality of life. This paper investigates HBOT and
its indications for use.
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The beneficial properties of hyperbaric oxygen are used for
purposes other than reducing decompression times and solving
diving-related accidents or gasses intoxications, and many
scientists highlight the beneficial results of such treatments. It is,
for example, the case of a paper called “Hyperbaric Oxygen
Therapy: An Overview”, written by doctors Gordon Slater, Martin
O’Malley, Tayla Slater, and Tandose Sambo.
In another article called “Chronicles of hyperbaric oxygen
treatment”, doctor Tahreem Fatima suggests that such therapies
enhance the anti-microbial effects of the immune system and have
an additive or synergistic effect with anti-microbial agents.
In their paper entitled “Hyperbaric Oxygen Therapy: Descriptive
review of the technology and current application in chronic wounds”,
doctors Babak Hajhosseini, Britta A. Kuehlmann, Clark A. Bonham,
Kathryn J. Kamperman, & Geoffrey C. Gurtner, make an
assessment of the hyperbaric oxygen treatments approved by the
Undersea and Hyperbaric Medical Society (UHMS). The
acknowledged applications of these procedures other than
resolving decompression sickness, arterial gas embolisms, and CO
poisoning intoxications can be listed as follows:
Acute traumatic peripheral ischemia
Crush injuries and suturing of severed limbs
Acute peripheral arterial insufficiency
Progressive necrotizing infections
Preparation and preservation of compromised skin grafts
Chronic refractory osteomyelitis
Diabetic wounds of the lower extremities
Failure of standard wound therapy
Note that some hospitals’ hyperbaric treatment chambers differ
from those used for diving activities by the fact that they are
square instead of rounded for better integration in the building and
easy access by people not in optimal physical condition. These
chambers are heavier than those we use for diving due to the
necessity to compensate for the non-optimal shape for
withstanding the pressure (rounded shapes are the most resistant),
and they are usually unable to withstand the same pressures as
rounded chambers. For example, the model below designed by CCC
Group (https://www.cccgroupinc.com/), a company based in San
Antonio, Texas, USA, is limited to three ATA.
Some other hospital chambers are rounded, except for the
extremities that are flat and provided with a square door, like
chambers used for tunneling. These chambers are very wide
compared with those we use for surface-supplied and saturation
diving; it is the case of the model below.
Of course, diving chambers can be used for such medical
treatments, and doctors may request to use them if hospital
facilities are not available and, by this fact, involve their operators.
Documents are available in our database to provide more
information regarding this aspect of using hyperbaric chambers.
Click on the button below to open the page where they are described
with the hyperlinks to open and download them.
They can also be accessed through Documents / Scientific papers.
Photo from “Chronicles of hyperbaric oxygen treatment” by doctor Tahreem Fatima